The three EEG (first, second rEEGs and ambulatory EEG) were interpreted by licensed neurologists recognized by the Royal College of Physicians and Surgeons of Canada and fully accredited by the Canadian Society of Clinical Neurophysiologists.
All the required information was available in this dataset, and further seizures were prospectively recorded. Methods: The study used a prospective cohort design with a total of 100 individuals with FSUS who underwent three modalities of EEG (first rEEG, second rEEG and Ambulatory EEG) and who were followed up for one year period. This study also aims to determine risk factors for further seizures among individuals with FSUS, including ED in the ambulatory EEG. This study aims to determine and compare the discriminative power, clinical predictive value, and global diagnostic accuracy of the ambulatory EEG compared with the first rEEG and second rEEG. However, the rEEG has low sensitivity, leaving patients and clinicians without a fast and accurate tool for the prognosis of further seizures. Furthermore, it is well-established that the presence of epileptiform discharge (ED) in the EEG increases the risk of further seizures among individuals with FSUS up to 3 times compared with individuals without such EEG changes. Background and objectives: Routine electroencephalography (rEEG) remains central in the prognosis of seizure recurrence among individuals with a First Single Unprovoked seizure (FSUS).
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